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Review
. 2012 Aug;12(4):485-503.
doi: 10.1586/erp.12.29.

Autism spectrum disorders: a review of measures for clinical, health services and cost-effectiveness applications

Nalin Payakachat  1 , J Mick Tilford, Erica Kovacs, Karen Kuhlthau
Affiliations
Review

Autism spectrum disorders: a review of measures for clinical, health services and cost-effectiveness applications

Nalin Payakachat et al. Expert Rev Pharmacoecon Outcomes Res. 2012 Aug.

Abstract

Autism spectrum disorders (ASDs) are characterized by impairments in social interaction, communication and behavioral functioning that can affect the health-related quality-of-life outcomes of the affected child and the family. ASDs have increased in prevalence, leading to a demand for improved understanding of the comparative effectiveness of different pharmacologic, behavioral, medical and alternative treatments for children as well as systems for providing services. This review describes outcome instruments that can be used for clinical, health services and cost-effectiveness applications. There is a pressing need to identify the most appropriate instruments for measuring health-related quality-of-life outcomes in this population. Studies evaluating the cost-effectiveness of interventions or treatments for children with ASDs using the cost per quality-adjusted life year metric are lacking. Researchers have the potential to contribute greatly to the field of autism by quantifying outcomes that can inform optimal treatment strategies.

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References

    1. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders DSM-IV TR. Amer Psychiatric Publishing; Arlington, VA, USA: 2000.
    1. Strock M. National Institutes of Mental Health, NIH, US Department of Health and Human Services; Report No NIH-04-5511. NIHMD; USA: 2004. Autism Spectrum Disorders (Pervasive Developmental Disorders)
    1. Lord C, Bishop SL. Autism spectrum disorders: diagnosis, prevalence, and services for children and families. Soc Pol Rep. 2010;24(2):1–25.
    1. Saulnier C, Quirmbach L, Klin A. Clinical evaluation of children with autism spectrum disorders. In: Hollander E, Kolevzon A, Coyle JT, editors. Textbook of Autism Spectrum Disorders. American Psychiatric Publishing, Inc; VA, USA: 2011. pp. 25–37.
    1. Lord C, Petkova E, Hus V, et al. A multisite study of the clinical diagnosis of different autism spectrum disorders. Arch Gen Psychiatry. 2012;69(3):306–313. Demonstrates site differences in bestestimate clinical diagnoses of autism spectrum disorder (ASD) subtypes even when standardized clinical instruments were used. The findings support the new diagnostic frameworks for ASDs. - PMC - PubMed

Websites

    1. American Psychiatric Association. [Accessed 16 July 2011];DSM-5: the future of psychiatric diagnosis. www.dsm5.org/proposedrevision/pages/proposedrevision.aspx?rid=94.
    1. Interagency Autism Coordinating Committee. [Accessed 16 July 2011];IACC strategic plan for autism spectrum disorder research. 2011 http://iacc.hhs.gov/strategic-plan/2011/index.shtml.
    1. NIH. [Accessed 8 March 2012];Patient-Reported Outcomes Measurement Information System: dynamic tools to measure health outcomes from the patient perspective. www.nihpromis.org.
    1. NIH. [Accessed 8 March 2012];Patient-Reported Outcomes Measurement Information System: PROs for children and young adults with disabilities. www.nihpromis.org/about/BostonUniversity.
    1. Johns Hopkins University. [Accessed 22 July 2011];Child Health and Illness Profile: a comprehensive assessment of health and functioning for children and adolescents. http://childhealthprofile.org.

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