Relationship of human urinary and plasma kinins to sodium-retaining steroids and plasma renin activity
- PMID: 229712
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Relationship of human urinary and plasma kinins to sodium-retaining steroids and plasma renin activity
Adv Exp Med Biol.
1979.
Abstract
In these studies we have shown that: 1. urinary kallikrein is an index of sodium-retaining steroid activity and may participate in the anti-natriuretic and kaliuretic effects of these hormones; 2. urinary kinin excretion is independent of changes in urinary kallikrein excretion; 3. levels of plasma bradykinin are highly correlated with levels of plasma renin activity probably because both respond to changes in extracellular fluid volume; and, 4. plasma bradykinin may act to antagonize angiotensin II to maintain normal blood pressure in hyper-reninemic states.
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