Review
doi: 10.1016/j.ntt.2012.08.006.
Epub 2012 Sep 3.
Zebrafish as potential model for developmental neurotoxicity testing: a mini review
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- PMID: 22971930
- DOI: 10.1016/j.ntt.2012.08.006
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Review
Zebrafish as potential model for developmental neurotoxicity testing: a mini review
Neurotoxicol Teratol.
2012 Nov-Dec.
Abstract
The zebrafish is a powerful toxicity model; biochemical assays can be combined with observations at a structural and functional level within one individual. This mini review summarises the potency of zebrafish as a model for developmental neurotoxicity screening, and its possibilities to investigate working mechanisms of toxicants. The use of zebrafish in toxicity research can ultimately lead to the refinement or reduction of animal use.
Copyright © 2012 Elsevier Inc. All rights reserved.
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