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Comment
. 2012 Sep 12;4(151):151ps15.
doi: 10.1126/scitranslmed.3004631.

Extrapolating from animals to humans

John P A Ioannidis  1
Affiliations
Comment

Extrapolating from animals to humans

John P A Ioannidis. Sci Transl Med. .

Abstract

Because of a variety of caveats, the safety and effectiveness of interventions in human subjects can only be speculated from animal studies. Careful synthesis of data from multiple animal studies is needed to begin to assess the likelihood of successful cross-species translation (Fay et al., this issue).

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