Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2012;9(9):e1001306.
doi: 10.1371/journal.pmed.1001306. Epub 2012 Sep 4.

Point-of-care testing for infectious diseases: diversity, complexity, and barriers in low- and middle-income countries

Affiliations

Point-of-care testing for infectious diseases: diversity, complexity, and barriers in low- and middle-income countries

Nitika Pant Pai et al. PLoS Med. 2012.

Abstract

Madhukar Pai and colleagues discuss a framework for envisioning how point-of-care testing can be applied to infectious diseases in low- and middle-income countries.

PubMed Disclaimer

Conflict of interest statement

No financial or industry conflicts. MP serves as a consultant for the Bill & Melinda Gates Foundation. BMGF had no involvement in this manuscript. NPP is an Academic Editor with PLOS ONE. MP is on the editorial boards of PLOS ONE and PLOS Medicine. The other authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Diversity of target product profiles, users, and settings within the spectrum of POC testing.
HBV, hepatitis B virus; HCV, hepatitis C virus; UTI, urinary tract infection; MRSA, methicillin-resistant staphylococcus aureus; C. diff, clostridium difficile; RDT, rapid diagnostic test; Strep A, group A streptococcus.

References

    1. Yager P, Domingo GJ, Gerdes J (2008) Point-of-care diagnostics for global health. Annu Rev Biomed Eng 10: 107–144. - PubMed
    1. Peeling RW, Mabey D (2010) Point-of-care tests for diagnosing infections in the developing world. Clin Microbiol Infect 16: 1062–1069. - PubMed
    1. Pai NP, Klein MB (2008) Are we ready for home-based, self-testing for HIV? Future HIV Therapy 2: 515–520.
    1. US Food and Drug Administration (2012) FDA approves first over-the-counter home-use rapid HIV test. FDA news release, 3 July 2012. Available: http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm310542.htm. Accessed 5 August 2012.
    1. Palamountain KM, Baker J, Cowan EP, Essajee S, Mazzola LT, et al. (2012) Perspectives on introduction and implementation of new point-of-care diagnostic tests. J Infect Dis 205 Suppl 2: S181–S190. - PMC - PubMed

Publication types