Crown-rump length discordance in twins in the first trimester and its correlation with perinatal complications
- PMID: 22973393
- PMCID: PMC3430049
Crown-rump length discordance in twins in the first trimester and its correlation with perinatal complications
Abstract
Background: A difference more than 15-40% in birth weight of twins can predict perinatal complications. As significant difference in twins growth has a very important effect on pregnancy and perinatal complications, this study aimed to evaluate crown-rump length discordance (ΔCRL) in the first trimester of pregnancy and its correlation with perinatal complications.
Methods: A total number of 118 women in the first trimester of twin pregnancy underwent ultrasound examination to measure ΔCRL. Then, at the time of delivery, perinatal complications in twins were recorded and the correlation between ΔCRL and perinatal complications were evaluated.
Results: Among 118 studied mothers with twin pregnancy, ΔCRL was normal (< 11%) in 96 cases (81.4%) and high (≥ 11%) in 22 cases (18.6%). Birth weight discordance was normal (< 20%) in 103 cases (87.3%) and above normal (≥ 20%) in 15 cases (12.7%). The results revealed a significant correlation between higher frequency of small for gestational age (SGA) and high ΔCRL (more than 11%) (p = 0.01).
Conclusions: Our study concluded that SGA has a significant relationship with high ΔCRL (> 11%).
Keywords: Crown-Rump Length; Discordance; Perinatal Complications; Twins; Ultrasound Examination.
Conflict of interest statement
References
-
- Tai J, Grobman WA. The association of crown-rump length discordance in twin gestations with adverse perinatal outcomes. Am J Obstet Gynecol. 2007;197(4):369–4. - PubMed
-
- Souter VL, Parisi MA, Nyholt DR, Kapur RP, Henders AK, Opheim KE, et al. A case of true hermaphroditism reveals an unusual mechanism of twinning. Hum Genet. 2007;121(2):179–85. - PubMed
-
- Golubovsky MD. Postzygotic diploidization of triploids as a source of unusual cases of mosaicism, chimerism and twinning. Hum Reprod. 2003;18(2):236–42. - PubMed
-
- Ewigman BG, Crane JP, Frigoletto FD, LeFevre ML, Bain RP, McNellis D. Effect of prenatal ultrasound screening on perinatal outcome. RADIUS Study Group. N Engl J Med. 1993;329(12):821–7. - PubMed
-
- Saari-Kemppainen A, Karjalainen O, Ylostalo P, Heinonen OP. Ultrasound screening and perinatal mortality: controlled trial of systematic one-stage screening in pregnancy.The Helsinki Ultrasound Trial. Lancet. 1990;336(8712):387–91. - PubMed
LinkOut - more resources
Full Text Sources
Research Materials