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Comment
. 2012;12(10):22-4.
doi: 10.1080/15265161.2012.699142.

The ever-evolving concept of clinical significance and the potential for sins of omission in genetic research

Gregory Costain  1 , Anne S Bassett
Affiliations
Comment

The ever-evolving concept of clinical significance and the potential for sins of omission in genetic research

Gregory Costain et al. Am J Bioeth. 2012.
No abstract available

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Comment on

References

    1. Ashida S, Koehly LM, Roberts JS, Chen CA, Hiraki S, Green RC. The role of disease perceptions and results sharing in psychological adaptation after genetic susceptibility testing: The REVEAL study. European Journal of Human Genetics. 2010;18(12):1296–1301. - PMC - PubMed
    1. Bloss CS, Schork NJ, Topol EJ. Effect of direct-to-consumer genomewide profiling to assess disease risk. New England Journal of Medicine. 2011;364(6):524–534. - PMC - PubMed
    1. Bollinger JM, Scott J, Dvoskin R, Kaufman D. Public preferences regarding the return of individual genetic research results: Findings from a qualitative focus group study. Genetics in Medicine. 2012;14(4):451–457. - PMC - PubMed
    1. Carvajal-Carmona LG. Challenges in the identification and use of rare disease-associated predisposition variants. Current Opinion in Genetics & Development. 2010;20(3):277–281. - PubMed
    1. Chan B, Facio FM, Eidem H, Hull SC, Biesecker LG, Berkman BE. Genomic inheritances: Disclosing individual research results from whole-exome sequencing to deceased participants’ relatives. American Journal of Bioethics. 2012;12(10):1–8. - PMC - PubMed