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. 2012 Oct 22;18(43):13629-32.
doi: 10.1002/chem.201202146. Epub 2012 Sep 13.

Single fluorescent probe displays a distinct response to Zn2+ and Cd2+

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Single fluorescent probe displays a distinct response to Zn2+ and Cd2+

Jiaoliang Wang et al. Chemistry. .

Abstract

Single probe, multiple targets: the design and synthesis of a new probe is described that can readily discriminate Zn(2+) and Cd(2+) with different fluorescence signals. The studies of Job's plot, mass spectroscopy, DFT calculations, and (1)H NMR spectroscopy reveal that the new probe has possible distinct binding modes to Zn(2+) and Cd(2+). This work may open up new opportunities for the development of single fluorescent probes that can sense multiple targets of interest.

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