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. 1979 Oct;38(5):450-5.
doi: 10.1136/ard.38.5.450.

Fate of herpes simplex virus in lymphocytes from inflammatory joint effusions. ii. Mechanisms of non-permissiveness

D J Appleford, A M Denman

Fate of herpes simplex virus in lymphocytes from inflammatory joint effusions. ii. Mechanisms of non-permissiveness

D J Appleford et al. Ann Rheum Dis. 1979 Oct.

Abstract

Mononuclear cells which were isolated from rheumatoid synovial effusions and cultured without prior separation failed to support the growth of herpes simplex virus (HSV). However, subpopulations of T lymphocytes separated on the basis of cell size or receptors for sheep red cells were, in isolation, permissive for this virus. Virus growth in these permissive cells was blocked by cocultivation with the remaining mononuclear cell populations.

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References

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    1. Ann Rheum Dis. 1979 Oct;38(5):443-9 - PubMed
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    1. Immunology. 1977 May;32(5):803-10 - PubMed
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