Lessons from korean capsule endoscopy multicenter studies

Abstract

Since its development, video capsule endoscopy (VCE) introduced a new area in the study of small bowel disease. We reviewed and discussed current issues from Korean capsule endoscopy multicenter studies. Main results are as follows: First, there was no significant difference in diagnostic yield according to the method of bowel preparation. Second, VCE represents a reliable and influential screening measure in patients with chronic unexplained abdominal pain and this technique could successfully alter the clinical course especially for patients with small bowel tumor. Third, the inter-observer variation in the expert group was lower than that in trainee group. Fourth, studies about the spontaneous capsule passage after retention showed 2.5% of retention rate and the size of lumen was an important factor of spontaneous passage. We need larger scale studies on the effect of bowel preparation methods on the diagnostic yield and further studies about the learning curve or unique capsule endoscopic findings for small intestinal diseases in Korean patients.

Keywords: Capsule endoscopy; Small bowel disease; Small intestine.

Fig. 1

Variable findings of tumors of small intestine detected by capsule endoscopy. (A) Subepithelial mass with intact covering mucosa and yellowish hue, diagnosed as lipoma. (B) Multiple epithelial mass with fungoid growth, diagnosed histologically as lymphoma. (C) Epithelial lesion with ulceration. (D) Subepithelial mass with superficial ulceration, diagnosed as gastrointestinal stromal tumor. (E) Multiple sessile polyps with fine-coarse surface texture and white hue, diagnosed as adenoma. (F) Protruding mass with superficial vascular and lymphatic dilatation.

Fig. 2

Flat lesions in the small bowel. (A) Erosions. (B) Aphthous ulcer. (C) Diverticulum. (D) Angiodysplasia.