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Review
. 2013 Feb;18(3-4):155-62.
doi: 10.1016/j.drudis.2012.09.001. Epub 2012 Sep 11.

Biomarkers of Parkinson's disease: current status and future perspectives

Jian Wang  1 , Jake G Hoekstra, Chuantao Zuo, Travis J Cook, Jing Zhang
Affiliations
Review

Biomarkers of Parkinson's disease: current status and future perspectives

Jian Wang et al. Drug Discov Today. 2013 Feb.

Abstract

This review summarizes major advances in biomarker discovery for diagnosis, differential diagnosis and progression of Parkinson's disease (PD), with emphasis on neuroimaging and biochemical markers. Potential strategies to develop biomarkers capable of predicting PD in the prodromal stage before the appearance of motor symptoms or correlating with nonmotor symptoms, an active area of research, are also discussed.

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Conflict of interest statement

Conflict of Interest: The authors report no conflicts of interest.

Figures

Figure 1
Figure 1. Imaging of dopamine transporter in different types of RBD patients
(a) Idiopathic RBD with normal DAT imaging and no signs for PD (male, 66 yrs); (b) Idiopathic RBD with reduction of DAT in imaging but no signs for PD; however, PD was confirmed clinically after follow up with left limbs affected at onset (male, 70 yrs); (C) Idiopathic RBD with reduction of DAT in imaging and PD (male, 71 yrs).
See this image and copyright information in PMC

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