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Editorial
. 2012 Oct 15;11(20):3713-4.
doi: 10.4161/cc.22112. Epub 2012 Sep 14.

Packaging host RNAs in small RNA viruses: an inevitable consequence of an error-prone polymerase?

Andrew Routh, Tatiana Domitrovic, John E Johnson
Editorial

Packaging host RNAs in small RNA viruses: an inevitable consequence of an error-prone polymerase?

Andrew Routh et al. Cell Cycle. .
No abstract available

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Figures

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Figure 1. Schematic representation of the capsid protein of flock house virus. Three sites have been previously identified as being critical for correct packaging of the viral genome into virus particles. These sites are highlighted in red in the crystal structure of the FHV capsid protein. Each of these sites is mutated to some degree (as indicated) within a population of virus particles due to the error-prone nature of the viral polymerase.
See this image and copyright information in PMC

Comment on

  • Routh A, Domitrovic T, Johnson JE. Host RNAs, including transposons, are encapsidated by a eukaryotic single-stranded RNA virus. Proc Natl Acad Sci U S A. 2012;109:1907–12. doi: 10.1073/pnas.1116168109. doi: 10.1073/pnas.1116168109

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