Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2013 May;270(5):1581-92.
doi: 10.1007/s00405-012-2170-9. Epub 2012 Sep 15.

Prognostic biological features in neck dissection specimens

Julia A Woolgar  1 , Asterios Triantafyllou, James S Lewis Jr, Jennifer Hunt, Michelle D Williams, Robert P Takes, Lester D R Thompson, Pieter J Slootweg, Kenneth O Devaney, Alfio Ferlito
Affiliations
Review

Prognostic biological features in neck dissection specimens

Julia A Woolgar et al. Eur Arch Otorhinolaryngol. 2013 May.

Abstract

The superior prognostic value offered by routine histopathological staging of neck dissections, as compared to clinical staging using palpation and modern imaging techniques, is well established in the literature concerning the management of squamous cell carcinoma of the head and neck. In this review, we discuss the definitions and criteria used in standardised routine histopathological reporting and explore additional potential nodal prognostic features. In addition, we critically appraise the value of immunohistochemistry, histochemistry, molecular and other non-morphological techniques and suggest tumour and host features that merit further investigations.

PubMed Disclaimer

References

    1. J Med Genet. 2003 Jan;40(1):25-33 - PubMed
    1. J Pathol. 2001 Jul;194(3):298-302 - PubMed
    1. Head Neck. 2010 Jun;32(6):714-22 - PubMed
    1. Head Neck. 2009 Oct;31(10):1346-53 - PubMed
    1. Oncogene. 2005 Feb 10;24(7):1244-51 - PubMed

MeSH terms

LinkOut - more resources