Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1990 Feb;58(2):557-62.
doi: 10.1128/iai.58.2.557-562.1990.

Passive immunization of chickens against Eimeria maxima infection with a monoclonal antibody developed against a gametocyte antigen

M Wallach  1 , G Pillemer, S Yarus, A Halabi, T Pugatsch, D Mencher
Affiliations

Passive immunization of chickens against Eimeria maxima infection with a monoclonal antibody developed against a gametocyte antigen

M Wallach et al. Infect Immun. 1990 Feb.

Abstract

Eimeria maxima gametocytes contain two major antigens with molecular masses of 56 and 82 kilodaltons (kDa) which are recognized by convalescent sera from immune chickens. Preparations enriched in these two antigens were used to immunize mice, and several monoclonal antibodies which specifically reacted with the 56-kDa antigen were produced. One of these monoclonal antibodies of the immunoglobulin M subclass, along with immune chicken sera raised against affinity-purified 56- and 82-kDa antigens, was used to passively immunize chicks. On the basis of the parameter of total oocyst output, it was found that these antibodies provided partial protection (40 to 50% inhibition) against E. maxima challenge infections.

PubMed Disclaimer

References

    1. Exp Parasitol. 1989 Jan;68(1):49-56 - PubMed
    1. Exp Parasitol. 1989 Feb;68(2):127-34 - PubMed
    1. J Immunol. 1983 Nov;131(5):2557-62 - PubMed
    1. EMBO J. 1983;2(2):167-72 - PubMed
    1. J Parasitol. 1966 Dec;52(6):1222 - PubMed

Publication types

LinkOut - more resources