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. 2012 Nov 5;8(11):595-6.
doi: 10.1038/nrneurol.2012.193.

Disease mechanisms in MS: the potassium channel KIR4.1--a potential autoantigen in MS

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Disease mechanisms in MS: the potassium channel KIR4.1--a potential autoantigen in MS

Michael K Racke. Nat Rev Neurol. .

Abstract

Multiple sclerosis is an inflammatory, demyelinating disease in which antigens of the myelin sheath have been considered the autoimmune target. A recent study suggests that the potassium channel KIR4.1 is another potential autoantigen in some patients with multiple sclerosis, and might also be a target in other demyelinating diseases.

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