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Comment
. 2012 Oct;8(10):812-3.
doi: 10.1038/nchembio.1066.

GhoSTly bacterial persisters

Laurence Van Melderen  1
Affiliations
Comment

GhoSTly bacterial persisters

Laurence Van Melderen. Nat Chem Biol. 2012 Oct.

Abstract

Bacterial persisters consist of a phenotypic subpopulation that survives antibiotic treatment, prolonging infection. The GhoT toxin from the newly discovered ghoS-ghoT toxin-antitoxin system contributes to persistence, most likely by interfering with bacterial inner membrane integrity.

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References

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