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Case Reports
. 2012 Sep 17:2012:bcr2012006954.
doi: 10.1136/bcr-2012-006954.

Endometrial stromal sarcoma of uterus with metastasis to the lung and brain

Ali Akhavan  1 , Forozan Shishebor, Mansour Moghimi, Fariba Binesh
Affiliations
Case Reports

Endometrial stromal sarcoma of uterus with metastasis to the lung and brain

Ali Akhavan et al. BMJ Case Rep. .

Abstract

Endometrial stromal sarcomas are rare tumours of the uterus and account for 10% of uterine sarcomas. Most of such tumours are low grade, although even these types can spread to the extrauterine areas; however, brain metastasis is very uncommon. This case report presents a 43-year-old Iranian woman with synchronous lung and brain metastases.

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Figures

Figure 1
Figure 1
MRI showing a lobulated mass lesion located in the left occipital lobe.
Figure 2
Figure 2
H&E showing malignant pleomorphic cells with numerous mitotic figures.
Figure 3
Figure 3
Vimentin.
Figure 4
Figure 4
Smooth muscle actin.
Figure 5
Figure 5
Oestrogen receptors.
Figure 6
Figure 6
CD10.
Figure 7
Figure 7
Ki-67.
Figure 8
Figure 8
CD34.
Figure 9
Figure 9
CT scanning showing multiple lung metastases.
See this image and copyright information in PMC

References

    1. Pekindil G, Tuncyurek O, Orguc S, et al. A case of endometrial stromal sarcoma with curvilinear calcification. Gynecol Oncol 2005;98:318–21. - PubMed
    1. Pink D, Lindner T, Mrozek A, et al. Harm or benefit of hormonal treatment in metastatic low-grade endometrial stromal sarcoma: single center experience with 10 cases and review of the literature. Gynecol Oncol 2006;101:464–9. - PubMed
    1. Ashraf-Ganjoei T, Behtash N, Shariat M, et al. Low grade endometrial stromal sarcoma of uterine corpus, a clinico-pathological and survey study in 14 cases. World J Surg Oncol 2006;9:50. - PMC - PubMed
    1. Malouf GG, Duclos J, Rey A, et al. Impact of adjuvant treatment modalities on the management of patients with stages I-II endometrial stromal sarcoma. Ann Oncol 2010;21:2102–6. - PubMed
    1. Kashi Z, Agha Meibodi SJ, Emadi SF. Endometrial stromal sarcoma presented with galactorrhea. Iran Red Crescent Med J 2009;11:334–6.

Publication types