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. 2012 Apr;33(2):71-9.
doi: 10.4103/0971-5851.99726.

Arecanut as an emerging etiology of oral cancers in India

Gunjan Shah  1 , Pankaj Chaturvedi, Sagar Vaishampayan
Affiliations

Arecanut as an emerging etiology of oral cancers in India

Gunjan Shah et al. Indian J Med Paediatr Oncol. 2012 Apr.

Abstract

Arecanut (AN) usage is widespread in Asian countries, especially India and Taiwan. The incidence of oral cancer is increasing day by day, but there is no exponential increase with tobacco usage. Especially in the country like Taiwan where betel quid mostly do not contain tobacco, AN can be correlated with the increased incidence of cancer. There are different studies in the literature about AN and oral cancer but none of them have concluded with the definite pathway for carcinogenesis. The present paper includes reviews of the literature for AN and oral cancer and summarizes the possible mechanisms associated with AN-induced carcinogenesis; and we have also tried to propose pathway of carcinogenesis.

Keywords: Arecanut; Asian countries; betel quid; carcinogenesis; oral cancer.

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Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
Molecular events
See this image and copyright information in PMC

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