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. 2012 Apr;16(2):71-4.
doi: 10.4103/0972-5229.99107.

Low molecular weight heparin in prophylaxis of deep vein thrombosis in Asian general surgical patients: A Kashmir experience

Tanveer Iqbal Dar  1 , Khursheed Alam Wani, Mohd Ashraf, Aijaz Malik, Sanjeed Ahmad, Tariq A Gojwari, Arshad Iqbal
Affiliations

Low molecular weight heparin in prophylaxis of deep vein thrombosis in Asian general surgical patients: A Kashmir experience

Tanveer Iqbal Dar et al. Indian J Crit Care Med. 2012 Apr.

Abstract

Background and objectives: Deep vein thrombosis (DVT) occurs at a lower rate in Asia than in the rest of the world. We wanted to study the significance and efficacy of low molecular weight heparin (LMWH) in prophylaxis of DVT in major general surgical patients in the Kashmir Valley (India, Asia) so as to make it a routine in our patients.

Patients and methods: This was a prospective study in which the effect of LMWH was compared with no prophylaxis.

Results: LMWHs are more effective than no prophylaxis in the prevention of DVT and pulmonary thromboembolism in highest-risk general surgical patients (odds ratio = 16.64; 95% confidence interval = 3.63-1130.03; P-value = 0.014).

Conclusion: LMWHs have a significant prophylactic effect on DVT in general surgical patients, with a higher benefit to risk ratio, and, in spite of the low incidence of DVT in Asia, its prophylaxis should routinely be considered in this part of the world as well, preferably in the form of LMWHs.

Keywords: Heparin; prophylaxis; thrombosis.

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Conflict of interest statement

Conflict of Interest: None declared.

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References

    1. Mark AC, Victor JD. Vascular diseases of the extremities. In: Braunwald E, Fauci AS, Kasper DL, Hauser SL, Longo DL, Jameson JL, editors. Harrison's Principles of Internal Medicine. 15th ed. New York City, U.S: McGraw Hill Companies Inc; 2001. pp. 1434–40.
    1. Lee LH, Gu KQ, Heng D. Deep vein thrombosis is not rare in Asia- The Singapore general hospital experience. Ann Acad Med Singapore. 2002;31:761–4. - PubMed
    1. Gutt C, Oniu T, Wolkener F, Mehrabi A, Mistry S, Buchler M. Prophylaxis and treatment of DVT in general surgery. Am J Surg. 2005;189:14–2. - PubMed
    1. Torngren S, Reiger A. Prophylaxis of deep vein thrombosis in colorectal surgery. Dis Colon Rectum. 1982;25:563–5. - PubMed
    1. Wille JP, Kjaergaard J, Thorup J. Postoperative thromboembolic complications despite heparin prophylaxis in major abdominal surgery. Ann Chir Gynaecol. 1985;74:130–3. - PubMed

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