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. 2012:2012:417821.
doi: 10.1155/2012/417821. Epub 2012 Sep 6.

Risk factors for recurrence of symptomatic common bile duct stones after cholecystectomy

Ju Hyun Oak  1 , Chang Nyol Paik, Woo Chul Chung, Kang-Moon Lee, Jin Mo Yang
Affiliations

Risk factors for recurrence of symptomatic common bile duct stones after cholecystectomy

Ju Hyun Oak et al. Gastroenterol Res Pract. 2012.

Abstract

Purpose. The recurrence of CBD stone is still observed in a considerable number of patients. The study was to evaluate the risk factors for recurrence of symptomatic CBD stone in patients who underwent cholecystectomy after the removal of CBD stone. Methods. The medical records of patients who underwent removal of CBD stone with subsequent cholecystectomy were reviewed. The risk factors for the recurrence of symptomatic CBD stone were compared between the recurrence and the nonrecurrence group. Results. The mean follow-up period was 40.6 months. The recurrence of symptomatic CBD stones was defined as the detection of bile duct stones no sooner than 6 months after complete clearance of CBD stones, based on symptoms or signs of biliary complication. 144 patients (68 males, 47.2%) were finally enrolled and their mean age was 59.8 (range: 26~86) years. The recurrence of CBD stone occurred in 15 patients (10.4%). The mean period until first recurrence was 25.9 months. The presence of type 1 or 2 periampullary diverticulum and multiple CBD stones were the independent risk factors. Conclusion. For the patients with type 1 or 2 periampullary diverticulum or multiple CBD stones, careful followup is needed for the risk in recurrence of symptomatic CBD stone.

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Figures

Figure 1
Figure 1
Actuarial probability curve of remaining free of recurrent symptomatic CBD stone after complete removal of the initial CBD stone with subsequent cholecystectomy. The patients with type 1 or 2 diverticulum versus those without diverticulum or those with type 3 diverticulum (80.5% versus 93.2%, resp.; P = 0.02, log-rank test) (- - -The patients with Type 1 or 2 diverticulum, or —the patients with type 3 diverticulum or without diverticulum).
Figure 2
Figure 2
Actuarial probability curve of remaining free of recurrent symptomatic CBD stone after complete removal of the initial CBD stone with subsequent cholecystectomy. The patients with single CBD stone versus those with multiple CBD stones (96.8% versus 84.0%, resp.; P = 0.04, log-rank test) (- - -The patients with multiple CBD stones, or —the patients with single CBD stone).
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