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Review
. 2013 Jul;28(7):1001-9.
doi: 10.1007/s00467-012-2260-3. Epub 2012 Sep 21.

Indications for use and safety of rituximab in childhood renal diseases

Kjell Tullus  1 , Stephen D Marks
Affiliations
Review

Indications for use and safety of rituximab in childhood renal diseases

Kjell Tullus et al. Pediatr Nephrol. 2013 Jul.

Abstract

Rituximab was initially developed for the treatment of patients with B cell lymphoma but has during the last decade proven to be quite effective in treating a range of kidney diseases including lupus nephritis, nephrotic syndrome, and also in different situations before and after a renal transplant. We will here review the scientific basis for the use of rituximab in children with renal diseases and give recommendations both regarding its clinical use and need for further research.

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