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. 2012:2012:184075.
doi: 10.1100/2012/184075. Epub 2012 Sep 10.

Gender differences and the trend in the acute myocardial infarction: a 10-year nationwide population-based analysis

Hung-Yu Yang  1 , Jen-Hung Huang, Chien-Yeh Hsu, Yi-Jen Chen
Affiliations

Gender differences and the trend in the acute myocardial infarction: a 10-year nationwide population-based analysis

Hung-Yu Yang et al. ScientificWorldJournal. 2012.

Abstract

It is not clear whether gender is associated with different hospitalization cost and lengths for acute myocardial infarction (AMI). We identified patients hospitalized for primary diagnosis of AMI with (STEMI) or without (NSTEMI) ST elevation from 1999 to 2008 through a national database containing 1,000,000 subjects. As compared to that in 1999~2000, total (0.35‰ versus 0.06‰, P < 0.001) and male (0.59‰ versus 0.07‰, P < 0.001) STEMI hospitalization percentages were decreased in 2007~2008, but female STEMI hospitalization percentages were not different from 1999 to 2008. However, NSTEMI hospitalization percentages were similar over the 10-year period. The hospitalization age for AMI, STEMI, and NSTEMI was increased over the 10-year period by 14, 9, and 7 years in male, and by 18, 18, and 21 years in female. The female and male hospitalization cost and lengths were similar in the period. As compared to nonmedical center, the hospitalization cost for STEMI in medical center was higher in male patients, but not in female patients, and the hospitalization cost for NSTEMI was higher in both male and female gender. We found significant differences between male and female, medical center and non-medical center, or STEMI and NSTEMI on medical care over the 10-year period.

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Figures

Figure 1
Figure 1
Hospitalization percentages of acute myocardial infarction (AMI, (a)), ST elevation MI (STEMI, (b)), or non-ST elevation MI (NSTEMI, (c)) from 1999 to 2008. *P < 0.05 versus 1999~2000, † P < 0.05 versus 2001~2002, # P < 0.05 versus 2003~2004, and § P < 0.05 versus 2005~2006.
Figure 2
Figure 2
Hospitalization age of total, male and female acute myocardial infarction (AMI, (a)), ST elevation MI (STEMI, (b)), or non-ST elevation MI (NSTEMI, (c)) from 1999 to 2008. *P < 0.05 versus 1999~2000, † P < 0.05 versus 2001~2002, and # P < 0.05 versus 2003~2004. Only the patients with first onset AMI within the year were included.
Figure 3
Figure 3
Hospitalization cost of total, male, and female acute myocardial infarction (AMI, (a)), ST elevation MI (STEMI, (b)), or non-ST elevation MI (NSTEMI, (c)) from 1999 to 2008. *P < 0.05 versus 1999~2000, † P < 0.05 versus 2001~2002, and § P < 0.05 versus 2005~2006.
Figure 4
Figure 4
Hospitalization lengths of total, male, and female acute myocardial infarction (AMI, (a)), ST elevation MI (STEMI, (b)), or non-ST elevation MI (NSTEMI, (c)) from 1999 to 2008.
Figure 5
Figure 5
Hospitalization age and lengths in higher (≥10000 NT dollar/day) and lower cost AMI patients from 1999 to 2008. Panel (a) shows the average age from higher and lower AMI hospitalization cost. Panel (b) shows the average hospitalization lengths from higher and lower AMI hospitalization cost. *P < 0.05 versus higher cost patients (≥10000 NT dollars/day). Only the patients with first onset AMI within the year were included.
Figure 6
Figure 6
The correlation of hospital length and total cost or daily cost in AMI patients. The hospital length was linearly correlated with total cost (a) and inversely correlated with daily cost (b).
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