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. 2012:2012:562594.
doi: 10.5402/2012/562594. Epub 2012 Sep 10.

Necrotizing enterocolitis in very low birth weight infants: a systemic review

Bhoomika K Patel  1 , Jigna S Shah
Affiliations

Necrotizing enterocolitis in very low birth weight infants: a systemic review

Bhoomika K Patel et al. ISRN Gastroenterol. 2012.

Abstract

Necrotizing enterocolitis (NEC) is the most common serious gastrointestinal disorder affecting very preterm or very low birth weight infants. The risk is inversely proportional to gestational age and weight at birth. Fetal growth restriction and compromise may be additional specific risk factors. Despite extensive research and animal studies etiopathogenesis, preventive strategies and management options remain controversial. The present paper reviews the literature for recent advances and newer insights for changing epidemiological trends, pathogenesis, role of inflammatory cytokines, and various preventive and management strategies.

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Figures

Figure 1
Figure 1
Pathogenesis of NEC.
See this image and copyright information in PMC

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