Regulatory T cell differentiation: turning harmful into useful
- PMID: 22999949
- DOI: 10.1016/j.immuni.2012.09.002
Regulatory T cell differentiation: turning harmful into useful
Abstract
In this issue of Immunity, Lee et al. (2012) demonstrate a surprisingly broad "window of opportunity" for regulatory T (Treg) cell induction and provide evidence for an avidity model of Treg cell differentiation versus deletion.
Copyright © 2012 Elsevier Inc. All rights reserved.
Comment on
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A broad range of self-reactivity drives thymic regulatory T cell selection to limit responses to self.Immunity. 2012 Sep 21;37(3):475-86. doi: 10.1016/j.immuni.2012.07.009. Epub 2012 Aug 23. Immunity. 2012. PMID: 22921379 Free PMC article.
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