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Comment
. 2012 Sep 21;37(3):443-4.
doi: 10.1016/j.immuni.2012.09.004.

Treg cells acquire new directions, cytokines navigate

Naganari Ohkura  1 , Shimon Sakaguchi
Affiliations
Free article
Comment

Treg cells acquire new directions, cytokines navigate

Naganari Ohkura et al. Immunity. .
Free article

Abstract

Foxp3(+) Treg cells express transcription factors normally expressed by specific T helper cells at sites of inflammation. In this issue of Immunity, Koch et al. (2012) and Hall et al. (2012) demonstrate that IFN-γ and IL-27 distinctly induces T-bet(+) Treg cells via STAT-1 transcription factor activation.

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