Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2012 Dec 18;24(48):6479-83.
doi: 10.1002/adma.201202687. Epub 2012 Sep 24.

Multicompartment intracellular self-expanding nanogel for targeted delivery of drug cocktail

Remant Bahadur K C  1 , Peisheng Xu
Affiliations

Multicompartment intracellular self-expanding nanogel for targeted delivery of drug cocktail

Remant Bahadur K C et al. Adv Mater. .

Abstract

A nano cocktail, NCPD, fabricated from a pH and redox dual responsive polymer shows a multicompartment structure. The NCPD nanogel is stable in physiological environments while intracellular spontaneous swelling and fast releasing its payload. NCPD displays much stronger synergism than its free drug counterpart, which suggests that NCPD could greatly attenuate the side effects of drug cocktails while boosting synergistic anticancer effects.

PubMed Disclaimer

Publication types

MeSH terms

LinkOut - more resources