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Review
. 2012 Sep-Oct;18(5):301-9.
doi: 10.4103/1319-3767.101123.

Hepatic encephalopathy

Wissam Bleibel  1 , Abdullah M S Al-Osaimi
Affiliations
Review

Hepatic encephalopathy

Wissam Bleibel et al. Saudi J Gastroenterol. 2012 Sep-Oct.

Abstract

Chronic liver disease and cirrhosis affect hundreds of millions of patients all over the world. The majority of patients with cirrhosis will eventually develop complications related to portal hypertension. One of these recurrent and difficult to treat complications is hepatic encephalopathy. Studies have indicated that overt hepatic encephalopathy affects 30 to 45% of patients with cirrhosis and a higher percentage may be affected by minimal degree of encephalopathy. All of these factors add to the impact of hepatic encephalopathy on the healthcare system and presents a major challenge to the gastroenterologist, hospitalist and primary care physician.

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Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
Classification of hepatic encephalopathy according to the working party at the 11th World Congress of Gastroenterology, Vienna, 1998.[6]
Figure 2
Figure 2
Algorithm for evaluation and treatment of HE
See this image and copyright information in PMC

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References

    1. Sanyal AJ, Mullen KD, Bass NM. The treatment of hepatic encephalopathy in the cirrhotic patient. Gastroenterol Hepatol (N Y) 2010;6(4 Suppl 8):1–12. - PMC - PubMed
    1. Bismuth M, Funakoshi N, Cadranel JF, Blanc P. Hepatic encephalopathy: From pathophysiology to therapeutic management. Eur J Gastroenterol Hepatol. 2011;23:8–22. - PubMed
    1. Butterworth RF. Editorial: Rifaximin and minimal hepatic encephalopathy. Am J Gastroenterol. 2011;106:317–8. - PubMed
    1. Seyan AS, Hughes RD, Shawcross DL. Changing face of hepatic encephalopathy: Role of inflammation and oxidative stress. World J Gastroenterol. 2010;16:3347–57. - PMC - PubMed
    1. McPhail MJ, Bajaj JS, Thomas HC, Taylor-Robinson SD. Pathogenesis and diagnosis of hepatic encephalopathy. Expert Rev Gastroenterol Hepatol. 2010;4:365–78. - PubMed

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