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. 2012:2012:259307.
doi: 10.1155/2012/259307. Epub 2012 Sep 13.

Plasmablastic lymphoma of gingiva mimicking a reactive lesion: a case report

Neeta Bagul  1 , G S Mamatha, Aditi Mahalle
Affiliations

Plasmablastic lymphoma of gingiva mimicking a reactive lesion: a case report

Neeta Bagul et al. Case Rep Dent. 2012.

Abstract

Oral plasmablastic lymphoma (PBL) is a rare malignancy, associated with HIV or other immunocompromised conditions. The lesion constituted a new subtype of diffuse large B-cell lymphoma and proposed a distinct entity based on its basic morphology, its clinical behaviour involving predominantly extramedullary sites (particularly oral cavity), and its limited antigenic phenotype data suggesting plasmacytic differentiation. Authors here report a case of apparently healthy individual aged 35 years, presenting one-month history of swelling associated with loosened teeth around upper anteriors. Following incisional biopsy, routine histopathologic and immunohistochemical studies, the diagnosis of plasmablastic lymphoma was given.

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Figures

Figure 1
Figure 1
Exophytic gingival growth in the maxillary anterior palatal region.
Figure 2
Figure 2
Interdental bone loss in relation to maxillary central and lateral incisors.
Figure 3
Figure 3
Diffuse large lymphoid cells with abundant eosinophilic cytoplasm, centrally or few eccentrically placed nuclei, and pleomorphic basophilic nucleoli (×40).
Figure 4
Figure 4
See this image and copyright information in PMC

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