Functional predictions from inference and observation in sequence-based inflammatory bowel disease research

doi:10.1186/gb4042

Comment

. 2012;13(9):169.

doi: 10.1186/gb4042.

Functional predictions from inference and observation in sequence-based inflammatory bowel disease research

Folker Meyer¹, William L Trimble, Eugene B Chang, Kim M Handley

Affiliations

PMID: 23013527
PMCID: PMC3491387
DOI: 10.1186/gb4042

Comment

Functional predictions from inference and observation in sequence-based inflammatory bowel disease research

Folker Meyer et al. Genome Biol. 2012.

. 2012;13(9):169.

doi: 10.1186/gb4042.

Authors

Folker Meyer¹, William L Trimble, Eugene B Chang, Kim M Handley

Affiliation

¹ Institute for Genomics and Systems Biology, Argonne National Laboratory, 9700 South Cass Avenue, Argonne, IL 60439, USA. folker@anl.gov

PMID: 23013527
PMCID: PMC3491387
DOI: 10.1186/gb4042

Abstract

Meta-omics approaches such as metagenomics, metatranscriptomics and metaproteogenomics have the potential to improve our understanding of how the human microbiome affects digestive health and disease.

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Dysfunction of the intestinal microbiome in inflammatory bowel disease and treatment.
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References

1. Loftus EV Jr. Clinical epidemiology of inflammatory bowel disease: Incidence, prevalence, and environmental influences. Gastroenterol. 2004;126:1504–1517. doi: 10.1053/j.gastro.2004.01.063. - DOI - PubMed
1. Fava F, Danese S. Intestinal microbiota in inflammatory bowel disease: Friend or foe?. World J Gastroenterol. 2011;17:557–566. doi: 10.3748/wjg.v17.i5.557. - DOI - PMC - PubMed
1. Waidmann M, Bechtold O, Frick J-S, Lehr H-A, Schubert S, Dobrindt U, Löffler J, Bohn E, Autenrieth IB. Bacteroides vulgatus protects against Escherichia coli-induced colitis in gnotobiotic Interleukin-2-deficient mice. Gastroenterol. 2003;125:162–177. doi: 10.1016/S0016-5085(03)00672-3. - DOI - PubMed
1. Eckburg PB, Bik EM, Bernstein CN, Purdom E, Dethlefsen L, Sargent M, Gill SR, Nelson KE, Relman DA. Diversity of the human intestinal microbial flora. Science. 2005;308:1635–1638. doi: 10.1126/science.1110591. - DOI - PMC - PubMed
1. Goodman AL, Kallstrom G, Faith JJ, Reyes A, Moore A, Dantas G, Gordon JI. Extensive personal human gut microbiota culture collections characterized and manipulated in gnotobiotic mice. Proc Nat Acad Sci USA. 2012. - DOI - PMC - PubMed

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[1] Loftus EV Jr. Clinical epidemiology of inflammatory bowel disease: Incidence, prevalence, and environmental influences. Gastroenterol. 2004;126:1504–1517. doi: 10.1053/j.gastro.2004.01.063. - DOI - PubMed

[2] Loftus EV Jr. Clinical epidemiology of inflammatory bowel disease: Incidence, prevalence, and environmental influences. Gastroenterol. 2004;126:1504–1517. doi: 10.1053/j.gastro.2004.01.063. - DOI - PubMed

[3] Fava F, Danese S. Intestinal microbiota in inflammatory bowel disease: Friend or foe?. World J Gastroenterol. 2011;17:557–566. doi: 10.3748/wjg.v17.i5.557. - DOI - PMC - PubMed

[4] Fava F, Danese S. Intestinal microbiota in inflammatory bowel disease: Friend or foe?. World J Gastroenterol. 2011;17:557–566. doi: 10.3748/wjg.v17.i5.557. - DOI - PMC - PubMed

[5] Waidmann M, Bechtold O, Frick J-S, Lehr H-A, Schubert S, Dobrindt U, Löffler J, Bohn E, Autenrieth IB. Bacteroides vulgatus protects against Escherichia coli-induced colitis in gnotobiotic Interleukin-2-deficient mice. Gastroenterol. 2003;125:162–177. doi: 10.1016/S0016-5085(03)00672-3. - DOI - PubMed

[6] Waidmann M, Bechtold O, Frick J-S, Lehr H-A, Schubert S, Dobrindt U, Löffler J, Bohn E, Autenrieth IB. Bacteroides vulgatus protects against Escherichia coli-induced colitis in gnotobiotic Interleukin-2-deficient mice. Gastroenterol. 2003;125:162–177. doi: 10.1016/S0016-5085(03)00672-3. - DOI - PubMed

[7] Eckburg PB, Bik EM, Bernstein CN, Purdom E, Dethlefsen L, Sargent M, Gill SR, Nelson KE, Relman DA. Diversity of the human intestinal microbial flora. Science. 2005;308:1635–1638. doi: 10.1126/science.1110591. - DOI - PMC - PubMed

[8] Eckburg PB, Bik EM, Bernstein CN, Purdom E, Dethlefsen L, Sargent M, Gill SR, Nelson KE, Relman DA. Diversity of the human intestinal microbial flora. Science. 2005;308:1635–1638. doi: 10.1126/science.1110591. - DOI - PMC - PubMed

[9] Goodman AL, Kallstrom G, Faith JJ, Reyes A, Moore A, Dantas G, Gordon JI. Extensive personal human gut microbiota culture collections characterized and manipulated in gnotobiotic mice. Proc Nat Acad Sci USA. 2012. - DOI - PMC - PubMed

[10] Goodman AL, Kallstrom G, Faith JJ, Reyes A, Moore A, Dantas G, Gordon JI. Extensive personal human gut microbiota culture collections characterized and manipulated in gnotobiotic mice. Proc Nat Acad Sci USA. 2012. - DOI - PMC - PubMed

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Functional predictions from inference and observation in sequence-based inflammatory bowel disease research

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Functional predictions from inference and observation in sequence-based inflammatory bowel disease research

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