Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 2013 Apr;17(2):208-15.
doi: 10.1111/j.1542-4758.2012.00756.x. Epub 2012 Sep 28.

Long-term effects of daily hemodialysis on vascular access outcomes: a prospective controlled study

Steven G Achinger  1 , T Alp Ikizler, Aihua Bian, Ayumi Shintani, Juan Carlos Ayus
Affiliations
Clinical Trial

Long-term effects of daily hemodialysis on vascular access outcomes: a prospective controlled study

Steven G Achinger et al. Hemodial Int. 2013 Apr.

Abstract

Daily hemodialysis has been associated with surrogate markers of improved survival among hemodialysis patients. A potential disadvantage of daily hemodialysis is that frequent vascular access cannulations may affect long-term vascular access patency. The study design was a 4-year, nonrandomized, contemporary control, prospective study of 77 subjects in either 3-h daily hemodialysis (six 3-h dialysis treatments weekly; n = 26) or conventional dialysis (three 4-h dialysis treatments weekly; n = 51). Outcomes of interest were vascular access procedures (fistulagram, thrombectomy and access revision). Total access procedures (fistulagram, thrombectomy and access revision) were 543.2 (95% confidence interval [CI]: 432.9, 673.0) per 1000 person-years in the conventional dialysis group vs. 400.8 (95% CI: 270.2, 572.4) per 1000 person-years in the daily hemodialysis dialysis group (incidence rate ratio = 0.74 with 95% CI: from 0.40 to 1.36, P = 0.33), after adjusting for age, gender, diabetes status, serum phosphorus, hemoglobin level and erythropoietin dose, there was no significant differences in incidence rate of total access procedures (P-value > 0.05). There was no difference in time to first access revision between the daily dialysis and the conventional dialysis groups after adjustment for covariates (hazard ratio = 0.99 95% CI: 0.42, 2.36, P = 0.96). Daily hemodialysis is not associated with increased vascular access complications, or increased vascular access failure rates.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Figure 2
Figure 2
Access procedure rate by treatment groups and procedure type.
Figure 3
Figure 3
See this image and copyright information in PMC

Similar articles

See all similar articles

References

    1. Ayus JC, Mizani MR, Achinger SG, Thadhani R, Go AS, Lee S. Effects of short daily versus conventional hemodialysis on left ventricular hypertrophy and inflammatory markers: a prospective, controlled study. J Am Soc Nephrol. 2005;9:2778–2788. - PubMed
    1. Ayus JC, Achinger SG, Mizani MR, et al. Phosphorus balance and mineral metabolism with 3 h daily hemodialysis. Kidney Int. 2007;71:336–342. - PubMed
    1. Achinger SG, Mizani MR, Ayus JC. Use of 3-hour daily hemodialysis and paricalcitol in patients with severe secondary hyperparathyroidism: A case series. Hemodial Int. 2010;14(2):193–199. - PubMed
    1. Traeger J, Galland R, Delawari E, Arkouche W, Hadden R. Six years’ experience with short daily hemodialysis: do the early improvements persist in the mid and long term? Hemodial Int. 2004;8:151–158. - PubMed
    1. Williams AW, Chebrolu SB, Ing TS, et al. Early clinical, quality-of-life, and biochemical changes of “daily hemodialysis” (6 dialyses per week) Am J Kidney Dis. 2004;43(1):90–102. - PubMed

Publication types