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. 1990 Jan;65(1):137-9.
doi: 10.1136/adc.65.1.137.

Platelet antigens in varicella associated thrombocytopenia

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Platelet antigens in varicella associated thrombocytopenia

J Winiarski. Arch Dis Child. 1990 Jan.

Abstract

Serum IgG or, predominantly, IgM antibody binding to electrophoretically separated normal platelet membrane protein antigens were detected by immunoblotting in five children with thrombocytopenia associated with varicella. Glycoproteins GPIb, GPIIb, GPIIIa, and other 25-260 kilodalton (kDa) proteins were identified as target antigens, suggesting a transient autoimmune mechanism causing the thrombocytopenia.

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