Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2013 Mar;99(3):218-22.
doi: 10.1002/bip.22132. Epub 2012 Sep 29.

The future of the Protein Data Bank

Affiliations
Review

The future of the Protein Data Bank

Helen M Berman et al. Biopolymers. 2013 Mar.

Abstract

The Worldwide Protein Data Bank (wwPDB) is the international collaboration that manages the deposition, processing and distribution of the PDB archive. The wwPDB's mission is to maintain a single archive of macromolecular structural data that are freely and publicly available to the global community. Its members [RCSB PDB (USA), PDBe (Europe), PDBj (Japan), and BMRB (USA)] host data-deposition sites and mirror the PDB ftp archive. To support future developments in structural biology, the wwPDB partners are addressing organizational, scientific, and technical challenges.

PubMed Disclaimer

Figures

FIGURE 1
FIGURE 1
Some examples of the diversity and complexity of modern structural biology: a) GroEL-GroES from PDB entry 1pcq; b) the nuclear pore complex (EMD-1097); c) ribosome from 3pio; d) archaeal proteasome gate from 2ku1; e) transcription factor IIB (TFIIB)/TATA box-binding protein from 1vol; f) potassium channel from 1bl8; g) beta-adrenergic GPCR from 2rh1; h) photosynthetic reaction center from 1prc.
FIGURE 2
FIGURE 2
Growth of the PDB archive: a) deposited and all released structures over time; b) number of chains per asymmetric unit released per year; c) polymeric molecular weight released per year; d) number of unique non-polymer ligands released per year.

References

    1. Berman H. Acta Crystallogr A: Foundations of Crystallography. 2008;64:88–95. - PubMed
    1. Bernstein FC, Koetzle TF, Williams GJB, Meyer EF, Jr, Brice MD, Rodgers JR, Kennard O, Shimanouchi T, Tasumi M. J Mol Biol. 1977;112:535–542. - PubMed
    1. Berman HM, Henrick K, Nakamura H. Nat Struct Biol. 2003;10:980. - PubMed
    1. Berman HM, Westbrook JD, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE. Nucleic Acids Research. 2000;28:235–242. - PMC - PubMed
    1. Velankar S, Alhroub Y, Best C, Caboche S, Conroy MJ, Dana JM, Fernandez Montecelo MA, van Ginkel G, Golovin A, Gore SP, Gutmanas A, Haslam P, Hendrickx PM, Heuson E, Hirshberg M, John M, Lagerstedt I, Mir S, Newman LE, Oldfield TJ, Patwardhan A, Rinaldi L, Sahni G, Sanz-Garcia E, Sen S, Slowley R, Suarez-Uruena A, Swaminathan GJ, Symmons MF, Vranken WF, Wainwright M, Kleywegt GJ. Nucleic Acids Res. 2012;40:D445–D452. - PMC - PubMed

Publication types

MeSH terms