doi: 10.1099/0022-1317-45-1-227.
Anticellular effects of 9-(2-hydroxyethoxymethyl) guanine against herpes simplex virus-transformed cells
- PMID: 230303
- DOI: 10.1099/0022-1317-45-1-227
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Anticellular effects of 9-(2-hydroxyethoxymethyl) guanine against herpes simplex virus-transformed cells
J Gen Virol.
1979 Oct.
Abstract
The guanine derivative 9-(2-hydroxyethoxymethyl) guanine (acycloguanosine), a potent inhibitor of herpes simplex virus (HSV) multiplication, was found to have marked anticellular activity against HSV-transformed thymidine kinase-positive cells. HSV type I-transformed cells were more sensitive to the drug than HSV type 2-transformed cells.
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