Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1990 Jan;149(4):232-4.
doi: 10.1007/BF02106278.

Daily profiles of salivary cortisol in hydrocortisone treated children with congenital adrenal hyperplasia

R Hampl  1 , L Foretová, J Sulcová, L Stárka
Affiliations

Daily profiles of salivary cortisol in hydrocortisone treated children with congenital adrenal hyperplasia

R Hampl et al. Eur J Pediatr. 1990 Jan.

Abstract

Daily profiles of salivary cortisol were determined in 14 cortisol-treated children with congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency, and in 5 healthy sibs. The results showed considerable individual variation irrespective of the dose of hormone, reflecting the different rates of cortisol metabolism and transport. Maximum salivary cortisol levels were reached 1-2 h following oral administration of hydrocortisone. The determination of salivary cortisol may be useful for optimal dosage timing, i.e. to imitate the daily rhythm of normal cortisol secretion.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Eur J Pediatr. 1980 May;133(3):259-67 - PubMed
    1. Ann N Y Acad Sci. 1985;458:193-202 - PubMed
    1. J Clin Endocrinol Metab. 1978 Mar;46(3):452-8 - PubMed
    1. J Clin Chem Clin Biochem. 1982 Oct;20(10):761-4 - PubMed
    1. Ann N Y Acad Sci. 1985;458:182-92 - PubMed

LinkOut - more resources