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Review
. 2012 May;27(2):81-7.
doi: 10.1053/j.tcam.2012.07.003. Epub 2012 Sep 12.

Endogenous anticoagulants

Affiliations
Review

Endogenous anticoagulants

Amy Kubier et al. Top Companion Anim Med. 2012 May.

Abstract

Blood coagulation is a complex and highly coordinated process that is constantly altered and impacted by procoagulant and anticoagulant "players." It is vital that these components work in concert to maintain a balance to keep coagulation in check. Several important endogenous anticoagulants will be discussed in this review including tissue factor pathway inhibitor, antithrombin, protein C, and protein S in origin, structure, mechanism of action, effects of deficiency, and current knowledge in veterinary medicine.

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