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. 2012 Oct;87(10):944-52.
doi: 10.1016/j.mayocp.2012.07.015.

Ideal cardiovascular health and mortality: Aerobics Center Longitudinal Study

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Ideal cardiovascular health and mortality: Aerobics Center Longitudinal Study

Enrique G Artero et al. Mayo Clin Proc. 2012 Oct.

Abstract

Objective: To analyze the relationship of ideal cardiovascular health to disease-specific death.

Patients and methods: We used data from the Aerobics Center Longitudinal Study from October 9, 1987, to March 3, 1999, to estimate the prevalence of ideal cardiovascular health in 11,993 individuals (24.3% women) and to examine its relationship with deaths from all causes, cardiovascular disease (CVD), and cancer.

Results: During a mean follow-up of 11.6 years, 305 deaths occurred: 70 (23.0%) from CVD and 127 (41.6%) from cancer. In the entire cohort, only 29 individuals (0.2%) had 7 ideal metrics. After adjusting for age, sex, examination year, alcohol intake, and parental history of CVD, risk of death due to CVD was 55% lower in those participants who met 3 or 4 ideal metrics (hazard ratio, 0.45; 95% confidence interval, 0.27-0.77) and 63% lower in those with 5 to 7 ideal metrics (hazard ratio, 0.37; 95% confidence interval, 0.15-0.95), compared with those who met 0 to 2 ideal metrics. Although not significant, there was also a trend toward lower risk of death due to all causes across incremental numbers of ideal metrics. No association was observed for deaths due to cancer.

Conclusion: The prevalence of ideal cardiovascular health was extremely low in a middle-aged cohort of men and women recruited between 1987 and 1999. The American Heart Association construct reflects well the subsequent risk of CVD, as reflected by graded CVD mortality in relation to the number of ideal metrics.

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Figures

FIGURE 1
FIGURE 1
Prevalence of poor, intermediate, and ideal levels for each of the 7 metrics of cardiovascular health at baseline.
FIGURE 2
FIGURE 2
Cardiovascular disease (CVD) death rates according to the number of ideal health behaviors and factors. There were no CVD-associated deaths in the combined group with 3 or 4 ideal behaviors and 3 ideal factors.

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References

    1. Roger V.L., Go A.S., Lloyd-Jones D.M., American Heart Association Statistics Committee and Stroke Statistics Subcommittee Heart disease and stroke statistics—2011 update: a report from the American Heart Association. Circulation. 2011;123(4):e18–e209. [published corrections appear in Circulation. 2011;123(6):e240 and Circulation. 2011;124(16)e.426] - PMC - PubMed
    1. Heidenreich P.A., Trogdon J.G., Khavjou O.A., American Heart Association Advocacy Coordinating Committee; Stroke Council; Council on Cardiovascular Radiology and Intervention; Council on Clinical Cardiology; Council on Epidemiology and Prevention; Council on Arteriosclerosis, Thrombosis and Vascular Biology; Council on Cardiopulmonary, Critical Care, Perioperative, and Resuscitation; Council on Cardiovascular Nursing; Council on the Kidney in Cardiovascular Disease; Council on Cardiovascular Surgery and Anesthesia; and Interdisciplinary Council on Quality of Care and Outcomes Research Forecasting the future of cardiovascular disease in the United States: a policy statement from the American Heart Association. Circulation. 2011;123(8):933–944. - PubMed
    1. Lloyd-Jones D.M., Leip E.P., Larson M.G. Prediction of lifetime risk for cardiovascular disease by risk factor burden at 50 years of age. Circulation. 2006;113(6):791–798. - PubMed
    1. Stamler J., Stamler R., Neaton J.D. Low risk-factor profile and long-term cardiovascular and noncardiovascular mortality and life expectancy: findings for 5 large cohorts of young adult and middle-aged men and women. JAMA. 1999;282(21):2012–2018. - PubMed
    1. Berry J.D., Liu K., Folsom A.R. Prevalence and progression of subclinical atherosclerosis in younger adults with low short-term but high lifetime estimated risk for cardiovascular disease: the Coronary Artery Risk Development in Young Adults Study and Multi-Ethnic Study of Atherosclerosis. Circulation. 2009;119(3):382–389. - PMC - PubMed

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