Asymmetric stem cell division: precision for robustness
- PMID: 23040475
- DOI: 10.1016/j.stem.2012.09.003
Asymmetric stem cell division: precision for robustness
Abstract
Asymmetric cell division (ACD) produces two daughter cells with distinct fates or characteristics. Many adult stem cells use ACD as a means of maintaining stem cell number and thus tissue homeostasis. Here, we review recent progress on ACD, discussing conservation between stem and non-stem cell systems, molecular mechanisms, and the biological meaning of ACD.
Copyright © 2012 Elsevier Inc. All rights reserved.
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