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Review
. 2012 Oct 5;11(4):461-9.
doi: 10.1016/j.stem.2012.09.003.

Asymmetric stem cell division: precision for robustness

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Free article
Review

Asymmetric stem cell division: precision for robustness

Mayu Inaba et al. Cell Stem Cell. .
Free article

Abstract

Asymmetric cell division (ACD) produces two daughter cells with distinct fates or characteristics. Many adult stem cells use ACD as a means of maintaining stem cell number and thus tissue homeostasis. Here, we review recent progress on ACD, discussing conservation between stem and non-stem cell systems, molecular mechanisms, and the biological meaning of ACD.

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