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Case Reports
. 2013 Mar;35(2):e88-90.
doi: 10.1097/MPH.0b013e318271c470.

Isolated primary testicular B lymphoblastic lymphoma: an unusual presentation

Alejandro V Garcia  1 , Bachir Alobeid, Jocelyn M Traina, Susie S Chen, Michael A Weiner, William Middlesworth
Affiliations
Case Reports

Isolated primary testicular B lymphoblastic lymphoma: an unusual presentation

Alejandro V Garcia et al. J Pediatr Hematol Oncol. 2013 Mar.

Erratum in

  • J Pediatr Hematol Oncol. 2016 Mar;38(2):162

Abstract

Acute lymphoblastic leukemia (ALL) is the most common cancer in children and adolescents. Clinical presentation often reflects bone marrow involvement and consequences of bone marrow failure. Microscopic involvement of the testis is rare, occurring in about 2% of cases. We present a case of a 3-year-old child who displayed unilateral macroorchidism as the only clinical symptom of ALL. Although the patient presented with localized disease, he was treated with systemic chemotherapy without recurrence. In this report, we review the current literature on ALL testicular involvement, diagnosis, and treatment.

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Figures

Figure 1
Figure 1
Scrotal doppler ultrasound. A. Asymmetrically enlarged hypoechoic left testicle compared to right. B. Left testicle with increased vascularity without focal mass.
Figure 2
Figure 2
Testicular biopsy demonstrating extensive and diffuse infiltrate of lymphoblasts, residual tubule, arrowed, (Haematoxylin & Eosin stain, ×100). Higher magnification, insert, H&E stain, x400
Figure 3
Figure 3
Flow cytometric analysis shows a population of lymphoblasts: CD19+/CD10+ (A), CD34+ (B), CD20− (C), and TdT+ (D).
See this image and copyright information in PMC

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