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. 2012 Nov 21;10(43):8587-9.
doi: 10.1039/c2ob26774h.

A cucurbit[8]uril sponge

Vijayakumar Ramalingam  1 , Sharon K Kwee, Lisa M Ryno, Adam R Urbach
Affiliations

A cucurbit[8]uril sponge

Vijayakumar Ramalingam et al. Org Biomol Chem. .

Abstract

This paper describes a convenient approach to quantitative removal of the synthetic host cucurbit[8]uril (Q8) from aqueous mixtures using a sepharose resin coated in memantine groups to selectively sequester Q8 in the presence of competing hosts and guests. The "Q8 sponge" can separate Q8 from Q6 and reverse the Q8-mediated dimerization of peptides.

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