Recommended screening and preventive practices for long-term survivors after hematopoietic cell transplantation
- PMID: 23049402
- PMCID: PMC3459383
- DOI: 10.5581/1516-8484.20120032
Recommended screening and preventive practices for long-term survivors after hematopoietic cell transplantation
Abstract
Advances in hematopoietic cell transplantation (HCT) technology and supportive care techniques have led to improvements in long-term survival after HCT. Emerging indications for transplantation, introduction of newer graft sources (e.g. umbilical cord blood) and transplantation of older patients using less intense conditioning regimens have also contributed to an increase in the number of HCT survivors. These survivors are at risk for developing late complications secondary to pre-, periand post-transplant exposures and risk-factors. Guidelines for screening and preventive practices for HCT survivors were published in 2006. An international group of transplant experts was convened in 2011 to review contemporary literature and update the recommendations while considering the changing practice of transplantation and international applicability of these guidelines. This review provides the updated recommendations for screening and preventive practices for pediatric and adult survivors of autologous and allogeneic HCT.
Keywords: Allogeneic; Autologous; Hematopoietic cell transplantation; Late complications; Prevention; Screening.
Conflict of interest statement
Conflict-of-interest disclosure: The authors declare no competing financial interest
References
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- Bhatia S, Francisco L, Carter A, Sun CL, Baker KS, Gurney JG, et al. Late mortality after allogeneic hematopoietic cell transplantation and functional status of long-term survivors: report from the Bone Marrow Transplant Survivor Study. Blood. 2007; 110(10): 3784-92 Comment in: Blood. 2008;111(3):1740-1 - PMC - PubMed
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