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Review
. 2012 Dec;10(4):286-95.
doi: 10.1007/s11914-012-0120-5.

Idiopathic hypercalciuria and bone health

Affiliations
Review

Idiopathic hypercalciuria and bone health

Laura E Ryan et al. Curr Osteoporos Rep. 2012 Dec.

Abstract

Calcium is an important participant in many physiologic processes including coagulation, cell membrane transfer, hormone release, neuromuscular activation, and myocardial contraction. The body cooperates in a sophisticated web of hormonally mediated interactions to maintain stable extracellular calcium levels. Calcium is vital for skeletal mineralization, and perturbations in extracellular calcium may be corrected at the expense of bone strength and integrity. The aim of this review is to delineate our current understanding of idiopathic hypercalciuria in the context of bone health, specifically its definition, etiology, epidemiology, laboratory evaluation, and potential therapeutic management.

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