Manipulation of expectancy and anxiety in placebo research and their effects on opioid-induced analgesia

Affiliations

¹ Department of Cognitive and Clinical Neuroscience, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, 68159 Mannheim, Germany. maike.mueller@zi-mannheim.de

Comment

Maike Mueller et al. J Neurosci. 2012.

. 2012 Oct 10;32(41):14051-2.

doi: 10.1523/JNEUROSCI.3756-12.2012.

¹ Department of Cognitive and Clinical Neuroscience, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, 68159 Mannheim, Germany. maike.mueller@zi-mannheim.de

No abstract available

Comment on

Dissociable influences of opiates and expectations on pain.
Atlas LY, Whittington RA, Lindquist MA, Wielgosz J, Sonty N, Wager TD. Atlas LY, et al. J Neurosci. 2012 Jun 6;32(23):8053-64. doi: 10.1523/JNEUROSCI.0383-12.2012. J Neurosci. 2012. PMID: 22674280 Free PMC article.

1. Amanzio M, Pollo A, Maggi G, Benedetti F. Response variability to analgesics: a role for non-specific activation of endogenous opioids. Pain. 2001;90:205–215. - PubMed
1. Atlas LY, Whittington RA, Lindquist MA, Wielgosz J, Sonty N, Wager TD. Dissociable influences of opiates and expectations on pain. J Neurosci. 2012;32:8053–8064. - PMC - PubMed
1. Benedetti F, Amanzio M, Maggi G. Potentiation of placebo analgesia by proglumide. Lancet. 1995;346:1231. - PubMed
1. Benedetti F, Pollo A, Lopiano L, Lanotte M, Vighetti S, Rainero I. Conscious expectation and unconscious conditioning in analgesic, motor, and hormonal placebo/nocebo responses. J Neurosci. 2003;23:4315–4323. - PMC - PubMed
1. Benedetti F, Carlino E, Pollo A. Hidden administration of drugs. Clin Pharmacol Ther. 2011;90:651–661. - PubMed