Host-pathogen crosstalking: the mastery of taking the helm of the host
- PMID: 23063005
- DOI: 10.1016/j.str.2012.09.006
Host-pathogen crosstalking: the mastery of taking the helm of the host
Abstract
How can pathogen proteins functionally hijack their hosts? In this issue of Structure, Aitio et al. reveal that the process involves coordinated intrinsic disorder in a short pathogen sequence that elegantly commandeers the tightly regulated cytoskeletal signaling in the host.
Copyright © 2012 Elsevier Ltd. All rights reserved.
Comment on
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Enterohaemorrhagic Escherichia coli exploits a tryptophan switch to hijack host f-actin assembly.Structure. 2012 Oct 10;20(10):1692-703. doi: 10.1016/j.str.2012.07.015. Epub 2012 Aug 23. Structure. 2012. PMID: 22921828 Free PMC article.
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