Regulatory T cells in preeclampsia: some answers, more questions?
- PMID: 23063658
- PMCID: PMC3509764
- DOI: 10.1016/j.ajpath.2012.09.020
Regulatory T cells in preeclampsia: some answers, more questions?
Abstract
This Commentary highlights the article by Hsu et al (in this issue) reporting an enrichment in induced regulatory T cells (iTregs) in normal pregnancy but not in preeclampsia, implicating iTreg defect as central to the pathogenesis of preeclampsia.
Copyright © 2012 American Society for Investigative Pathology. Published by Elsevier Inc. All rights reserved.
Comment on
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Altered decidual DC-SIGN+ antigen-presenting cells and impaired regulatory T-cell induction in preeclampsia.Am J Pathol. 2012 Dec;181(6):2149-60. doi: 10.1016/j.ajpath.2012.08.032. Epub 2012 Oct 9. Am J Pathol. 2012. PMID: 23063509
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