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. 2012 Jul-Aug;30(4 Suppl 73):S112-5.
Epub 2012 Nov 20.

Treat-to-target in systemic lupus erythematosus: where are we today?

Marta Mosca  1 , Dimitrios T Boumpas, Ian N Bruce, Ricard Cervera, Laszlo Czirjak, Thomas Dörner, Frédéric Houssiau, Soren Jacobsen, Matthias Schneider, Josef S Smolen, Alexandre E Voskuyl, Ronald F van Vollenhoven
Affiliations
  • PMID: 23072706

Treat-to-target in systemic lupus erythematosus: where are we today?

Marta Mosca et al. Clin Exp Rheumatol. 2012 Jul-Aug.

Abstract

Multiple clinical trials performed over twenty years in the treatment of rheumatoid arthritis (RA) have clearly demonstrated that patients have better outcomes if their disease activity at each time-point for follow-up includes a pre-specified target. A European SLE expert panel met in Zurich on May 8, 2012 to discuss whether a treat-to-target approach could be applied in the treatment of systemic lupus erythematosus (SLE) (T2T/SLE), define a research agenda, and establish a plan for moving forward. In the present paper, observations raised at the meeting and literature data on potential therapeutic targets are reported. The working group on T2T/SLE will continue work over the coming year.

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