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Review
. 2012 Nov;13(11):743-7.
doi: 10.1038/nrm3459. Epub 2012 Oct 17.

New dimensions in cell migration

Peter Friedl  1 , Erik Sahai, Stephen Weiss, Kenneth M Yamada
Affiliations
Review

New dimensions in cell migration

Peter Friedl et al. Nat Rev Mol Cell Biol. 2012 Nov.

Abstract

Studies of cell migration in three-dimensional (3D) cell culture systems and in vivo have revealed several differences when compared with cell migration in two dimensions, including their morphology and mechanical and signalling control. Here, researchers assess the contribution of 3D models to our understanding of cell migration, both in terms of the mechanisms used to drive single cell and collective cell migration and how migrating cells respond to a changing environment in vivo.

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References

    1. J Cell Sci. 2012 Jul 1;125(Pt 13):3015-24 - PubMed
    1. Nature. 2008 May 1;453(7191):51-5 - PubMed
    1. Nat Rev Mol Cell Biol. 2009 Jul;10(7):445-57 - PubMed
    1. Annu Rev Cell Dev Biol. 2006;22:287-309 - PubMed
    1. Histochem Cell Biol. 2008 Dec;130(6):1147-54 - PubMed

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