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Review
. 2013 Jan;35(1):1-13.
doi: 10.1097/MPH.0b013e318271f457.

ITP in children: pathophysiology and current treatment approaches

John A D'Orazio  1 , Jessica Neely, Nina Farhoudi
Affiliations
Review

ITP in children: pathophysiology and current treatment approaches

John A D'Orazio et al. J Pediatr Hematol Oncol. 2013 Jan.

Abstract

Primary immune thrombocytopenia (ITP) is one of the most common bleeding disorders of childhood. In most cases, it presents with sudden widespread bruising and petechiae in an otherwise well child. Thought to be mainly a disorder of antibody-mediated platelet destruction, ITP can be self-limited or develop into a chronic condition. In this review, we discuss current concepts of the pathophysiology and treatment approaches to pediatric ITP.

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Comment in

  • ITP: the dilemma of treatment.
    Rajendran A, Bansal D. Rajendran A, et al. J Pediatr Hematol Oncol. 2014 Nov;36(8):666. doi: 10.1097/MPH.0b013e31829cda32. J Pediatr Hematol Oncol. 2014. PMID: 23799520 No abstract available.

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