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. 1990 Jan;43(1):1-7.
doi: 10.7164/antibiotics.43.1.

FR109615, a new antifungal antibiotic from Streptomyces setonii. Taxonomy, fermentation, isolation, physico-chemical properties and biological activity

T Iwamoto  1 , E Tsujii, M Ezaki, A Fujie, S Hashimoto, M Okuhara, M Kohsaka, H Imanaka, K Kawabata, Y Inamoto, et al.
Affiliations
Free article

FR109615, a new antifungal antibiotic from Streptomyces setonii. Taxonomy, fermentation, isolation, physico-chemical properties and biological activity

T Iwamoto et al. J Antibiot (Tokyo). 1990 Jan.
Free article

Abstract

FR109615, a new antibiotic active against Candida, was isolated from Streptomyces setonii No. 7562. Based on the spectroscopic data, the structure of FR109615 was elucidated as cis-2-aminocyclopentane-1-carboxylic acid (1). The compound showed the excellent in vivo efficacy in a generalized infection test of mice.

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