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. 2012 Dec;102(12):2360-6.
doi: 10.2105/AJPH.2011.300589. Epub 2012 Oct 18.

Repeated job strain and the risk of depression: longitudinal analyses from the Whitehall II study

Stephen A Stansfeld  1 , Martin J Shipley, Jenny Head, Rebecca Fuhrer
Affiliations

Repeated job strain and the risk of depression: longitudinal analyses from the Whitehall II study

Stephen A Stansfeld et al. Am J Public Health. 2012 Dec.

Abstract

Objectives: We addressed whether repeated job strain and low work social support increase the risk of major depressive disorder (MDD).

Methods: We used work characteristics from Karasek's Job Strain model, measured on 3 occasions over 10 years in a cohort of 7732 British civil servants, to predict subsequent onset of MDD with the Composite International Diagnostic Interview.

Results: Repeated job strain was associated with increased risk of MDD (odds ratio [OR] = 2.19; 95% confidence interval [CI] = 1.48, 3.26; high job strain on 2 of 3 occasions vs none) in a fully adjusted model. Repeated low work social support was associated with MDD (OR = 1.61; 95% CI = 1.10, 2.37; low work social support on 2 of 3 occasions vs none). Repeated job strain remained associated with MDD after adjustment for earlier psychological distress.

Conclusions: Demonstration of an increased association for repeated job strain adds to the evidence that job strain is a risk factor for depression. Recognition and alleviation of job strain through work reorganization and staff training could reduce depression in employees.

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References

    1. Kessler RC, Berglund P, Demler Oet al.National Comorbidity Survey replication: the epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R). JAMA. 2003;289(23):3095–3105 - PubMed
    1. Wells KB, Stewart A, Hays RDet al.The functioning and well-being of depressed patients. Results from the Medical Outcomes Study. JAMA. 1989;262(7):914–919 - PubMed
    1. Kessler RC, Frank RG. The impact of psychiatric disorders on work loss days. Psychol Med. 1997;27(4):861–873 - PubMed
    1. Goetzel RZ, Long SR, Ozminkowski RJ, Hawkins K, Wang S, Lynch W. Health, absence, disability, and presenteeism cost estimates of certain physical and mental health conditions affecting U.S. employers. J Occup Environ Med. 2004;46(4):398–412 - PubMed
    1. Wang PS, Simon G, Kessler RC. The economic burden of depression and the cost-effectiveness of treatment. Int J Methods Psychiatr Res. 2003;12(1):22–33 - PMC - PubMed

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