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. 2012 Dec;84(12):1980-4.
doi: 10.1002/jmv.23401.

Surveillance of 16 respiratory viruses in patients with influenza-like illness in Nanjing, China

Xiang Huo  1 , Yuanfang Qin, Xian Qi, Rongqiang Zu, Fenyang Tang, Liang Li, Zhibin Hu, Fengcai Zhu
Affiliations

Surveillance of 16 respiratory viruses in patients with influenza-like illness in Nanjing, China

Xiang Huo et al. J Med Virol. 2012 Dec.

Abstract

Much less is known about the etiology of influenza-like illness in China. A continuous surveillance of 16 respiratory viruses was conducted from November 2010 to October 2011 of outpatients with influenza-like illness in Nanjing, China. The two largest general hospitals and a provincial virus laboratory in Nanjing participated in this study. Throat swabs were collected from outpatients during medical visits for influenza-like illness and were tested for 16 respiratory viruses using PCR. Three hundred seventeen viruses were detected in samples from 246 (50.6%) patients with influenza-like illness. The viruses found mostly commonly were influenza, rhinovirus, hCoV HKU1, and adenovirus. The identification rates of respiratory viruses differed significantly among different sampling seasons (P = 0.0002). The rates of influenza A and hCoV HKU1 were much higher during the influenza-like illness winter peak than during the influenza-like illness summer peak and other months. Co-infections were detected in 57 (11.7%) patients and were found most commonly in adults older than 60 years. RSV was detected in 5.9% and 2.6% of patients who were 0-5 and 6-15 years old, respectively, but was not detected in other age groups. This study confirmed that multiple respiratory viruses may circulate concurrently in the population and account for a large proportion of influenza-like illness. In addition to influenza virus, hCoV HKU1 may be associated with the influenza-like illness winter peak in Nanjing, China.

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Figures

Figure 1
Figure 1
Viral etiology of ILI patients and overall positive rates of respiratory viruses by ILI seasons.
See this image and copyright information in PMC

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